Here is a good one for you... Totally reproducible on Windows 10 and Windows 7. On PC or laptops. Nvidia or AMD video cards. Steps to reproduce: Open the achievements window. Scroll down and open one of the larger "Collections" achievements Position your mouse over one of the collections and click (it should open normally) Hold your mouse very still (or pick your mouse up off the table) and scroll down. Scroll down (or up) so a new collections is directly under your mouse pointer. Click to open it*... Note that the sub-catigory does *not* open Click again (without moving your mouse) and it opens as expected. scrolling to a new achievement (without moving your mouse) will result in the first click not working again. (* if it opens, you have moved your mouse) Super simple work-a-around... don't be lazy (like me) and jiggle your mouse while scrolling. I think I found another place where this can happen but I cannot recall atm. Enjoy!
Just tried again today and still happening. The slayer achievements is another good spot to "experience" this bug.