Is "Miraguls Nightmare" zone supposed to look like this? I remember when HoT first came out, it was all colourful. maybe a year later, it was the same for me... but it look like this on my Brothers computer. All of a sudden, i zone in for the first time in 2ish years it looks like this.
Options Window, Display Tab, Advanced Button. You're looking for the checkbox that says Enable Post Effects, which will affect how you see this zone (among other effects). The zone is intended to start off in black and white, which makes things like the black oozes hard to see. As you complete quests in the zone, you start getting color to fade back in.
There are other places Post Effects get used. Quests and Raids with bombs that tint your screen red if you are standing in the blast radius. I find it useful to leave enabled more often than not.
If i recall, a lot of missions and content in HoT went post effect crazy. I recall the lower hot group mission also had post effects change your screen color in each of the 4 main rooms updates take place at. I usually turned it off just to avoid the color changes.