Not game breaking but I've come across a couple of issues in the solo mission. First if you super speed into the room, you can actually end up out of the dome after the cut scene and effectively can't fight the boss without leaving the instance. I would think an entrance would be an easy enough fix for that. Second I've noticed that the heal barrel is often visible in the cut scene but gone once the fight starts. I'm not sure but I suspect it's getting caught outside the dome.